Acute liver failure following therapeutic paracetamol administration in patients with muscular dystrophies

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Acute liver necrosis following overdose of paracetamol.

A woman aged 30, an inmate of a mental institution, was admitted to hospital two hours after ingesting at least 50 paracetamol tablets. She had been discovered while still swallowing some of the drug, and gastric lavage was carried out almost immediately. She had been under psychiatric care since adolescence and had received various drug therapies. Currently she was taking nortriptyline, 25 mg....

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Acute liver failure in a term neonate after repeated paracetamol administration

OBJECTIVE Severe hepatotoxicity caused by paracetamol is rare in neonates. We report a case of paracetamol-induced acute liver failure in a term neonate. CASE DESCRIPTION A 26-day-old boy was admitted with intestinal bleeding, shock signs, slight liver enlargement, coagulopathy, metabolic acidosis (pH=7.21; bicarbonate: 7.1 mEq/L), hypoglycemia (18 mg/dL), increased serum aminotransferase act...

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Acute lung injury in fulminant hepatic failure following paracetamol poisoning.

BACKGROUND There is little information on the incidence of acute lung injury or changes in the pulmonary circulation in acute liver failure. The aim of this study was to record the incidence of acute lung injury in fulminant hepatic failure caused by paracetamol poisoning, to document the associated pulmonary circulatory changes, and to assess the impact of lung injury on patient outcome. MET...

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Acute Liver Failure Caused by Paracetamol Toxicity: a Case Report

Acute liver failure (ALF) is the clinical manifestation of sudden and severe hepatic injury. It is a rare disorder, with an incidence between one and six cases per million people every year in the developed world, and it has a high mortality rate. There are many definitions of ALF, but it is mainly characterised by the presence of encephalopathy during the course of fulminant hepatitis in a pat...

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Results of liver transplantation in patients with acute liver failure due to Amanita phalloides and paracetamol (acetaminophen) intoxication

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ژورنال

عنوان ژورنال: Anaesthesia

سال: 2007

ISSN: 0003-2409,1365-2044

DOI: 10.1111/j.1365-2044.2007.05340.x